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Global Orphan and Rare Dermatology Drugs Market to 2024 – An Increasingly Competitive Landscape as New Companies Enter the Market with Novel Products, Driving Strong Market Growth

  • Published: Sep-2018
  • Report Code: GBIHC481MR
  • Report Format: pdf


Dermatology is a highly diverse therapy area, in terms of severity and clinical presentation, which deals with diseases of the skin, hair and nails. Whilst an orphan disease is a disease that is neglected in terms of research and funding and in the US, a disease is considered to be rare if it affects fewer than 200,000 people. Many orphan and rare dermatology disorders are associated with significant quality of life impairments, particularly if the disease is insufficiently controlled. In particular, disease visibility can have a profoundly negative impact on patient confidence. However, the current therapeutics market is a highly genericized therapy area and there exists a significant unmet need for more efficacious and safer treatment options that treat the underlying causes of disease as opposed to managing the symptoms. This report covers all orphan and rare dermatology disorders, but there is a particular focus on six key diseases, systemic sclerosis (scleroderma), alopecia, epidermolysis bullosa, pemphigus vulgaris, vitiligo and cutaneous lupus erythematosus, as these conditions have the largest pipelines within the therapy area. The premium product market size for orphan and rare dermatology therapeutics was valued at $1.64 billion in 2017 and it is expected to grow at a compound annual growth rate (CAGR) of 20.5% to $6.07 billion in 2024.


  • The orphan and rare dermatology market landscape is expected to change and grow. Novel targets are expected to enter the market and drive market growth with a move towards disease modifying drugs instead of drugs which manage symptoms.

  • Overall, there are 262 orphan and rare dermatology products in the pipeline.

  • Which molecular targets are most prominent within the pipeline?

  • How do the key indications differ in terms of molecule type?

  • How does the composition of the pipeline compare with that of the existing market?

  • What mechanisms of action are most common for pipeline drugs?

  • The premium products market size for orphan and rare dermatology therapeutics is expected to grow, from $1.64 billion in 2017 to $6.07 billion in 2024, at a CAGR of 20.5%.

  • Which products will contribute to market growth most, and will any achieve blockbuster status?

  • Will the current market leaders retain their dominance over the forecast period, and how is their revenue share of the orphan and rare dermatology market set to change?

  • What CAGR will these companies register in the forecast period?

  • How many strategic consolidations have been completed in the past decade?

  • Which types of assets attract the largest deal values?

Reasons To Buy

  • Understand the current clinical and commercial landscape by considering disease pathogenesis, diagnosis, prognosis and the treatment options available at each stage of diagnosis for the six key indications.

  • Visualize the composition of the orphan and rare dermatology market overall and across each key indication, in terms of dominant molecule types and targets, highlighting the key commercial assets and players.

  • Identify trends and developments, in terms of molecule type and molecular target, within the overall orphan and rare dermatology pipeline, as well as for each of the six key indications.

  • Understand the growth in patient epidemiology and market revenues for the orphan and rare dermatology market globally, and across the key players and product types.

  • Consider market opportunities and potential risks by examining the incentives and challenges of drug development within the orphan market space and the trends in clinical trial duration and size, as well as clinical trial failure rates, by stage of development, molecule type and molecular target.

  • Recognize how the evolving treatment landscape will drive market growth to 2024 and understand the contributions that different products, molecular targets and companies will make to this growth.

  • Identify commercial opportunities in the orphan and rare dermatology deals landscape by analyzing trends in licensing and co-development deals.

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