List of Figures
Figure 1: Epilepsy Therapeutics Market, Patient Distribution in APAC 10
Figure 2: Summary of the Pathophysiology of Seizures by Net Increased Neuronal Excitation 16
Figure 3: Algorithm for investigation of patient presenting with seizure 18
Figure 4: Algorithm for Choice of AED for New-Onset Epilepsy Patients 26
Figure 5: Treatment Algorithm for Status Epilepticus in Australia 27
Figure 6: Epilepsy Therapeutics Market, Comparative Efficacy and Safety Heatmap for Marketed Products 43
Figure 7: Pipeline for Epilepsy Therapeutics, Global, 2018 45
Figure 8: Pipeline for Epilepsy Therapeutics by Molecular Target, Global, 2018 47
Figure 9: Epilepsy Therapeutics Market, APAC, ZX008 Forecast ($m), 2020–2024 50
Figure 10: Epilepsy Therapeutics Market, APAC, Cenobamate Forecast ($m), 2020–2024 51
Figure 11: Epilepsy Therapeutics Market, Comparative Efficacy and Safety Heatmap for Pipeline Products 52
Figure 12: Epilepsy Therapeutics Market, Competitor Matrix for Epilepsy Marketed and Pipeline Products 53
Figure 13: Epilepsy Therapeutics, Global, Average Clinical Trial Failure Rate (%), 2007–2017 55
Figure 14: Epilepsy Therapeutics, Global, Clinical Trial Failure Rates by Molecular Target (%), 2007–2017 56
Figure 15: Epilepsy Therapeutics, Global, Clinical Trial Size per Product by Molecule Type (participants), 2007–2017 57
Figure 16: Epilepsy Therapeutics, Global, Clinical Trial Size per Product by Molecular Target (participants), 2007–2017 58
Figure 17: Epilepsy Therapeutics, Global, Clinical Trial Size per Trial by Molecule Type (participants), 2007–2017 59
Figure 18: Epilepsy Therapeutics, Global, Clinical Trial Size per Trial by Molecular Target (participants), 2007–2017 60
Figure 19: Epilepsy Therapeutics, Global, Clinical Trial Duration by Molecule Type (months), 2007–2017 61
Figure 20: Epilepsy Therapeutics, Global, Clinical Trial Duration by Molecular Target (months), 2007–2017 62
Figure 21: Epilepsy Therapeutics Market, Global, Comparison of Average Trial Metrics by Phase and Molecule Type 62
Figure 22: Epilepsy Therapeutics Market, Global, Comparison of Average Trial Metrics by Phase and Molecular Target 63
Figure 23: Epilepsy Therapeutics Market, Asia-Pacific, Treatment Patterns (million), 2017–2024 65
Figure 24: Epilepsy Therapeutics Market, APAC, Market Size ($m), 2017–2024 66
Figure 25: Epilepsy Therapeutics Market, India, Treatment Patterns (million), 2017–2024 67
Figure 26: Epilepsy Therapeutics Market, India, Annual Cost of Therapy ($), 2017–2024 69
Figure 27: Epilepsy Therapeutics Market, India, Market Size ($m), 2017–2024 70
Figure 28: Epilepsy Therapeutics Market, China, Treatment Patterns (million), 2017–2024 71
Figure 29: Epilepsy Therapeutics Market, China, Annual Cost of Therapy ($), 2017–2024 72
Figure 30: Epilepsy Therapeutics Market, China, Market Size ($m), 2017–2024 73
Figure 31: Epilepsy Therapeutics Market, Australia, Treatment Patterns (‘000), 2017–2024 74
Figure 32: Epilepsy Therapeutics Market, Australia, Annual Cost of Therapy ($), 2017–2024 75
Figure 33: Epilepsy Therapeutics Market, Australia, Market Size ($m), 2017–2024 76
Figure 34: Epilepsy Therapeutics Market, South Korea, Treatment Patterns (‘000), 2017–2024 77
Figure 35: Epilepsy Therapeutics Market, South Korea, Annual Cost of Therapy ($), 2017–2024 78
Figure 36: Epilepsy Therapeutics Market, South Korea, Market Size ($m), 2017–2024 79
Figure 37: Epilepsy Therapeutics Market, Japan, Treatment Patterns (000), 2017–2024 80
Figure 38: Epilepsy Therapeutics Market, Japan, Annual Cost of Therapy ($), 2017–2024 81
Figure 39: Epilepsy Therapeutics Market, Japan, Market Size ($m), 2017–2024 82
Figure 40: Epilepsy Therapeutics Market, Global, Licensing Deals By Region And Value, 2007–2018 86
Figure 41: Epilepsy Therapeutics Market, Global, Number of Disclosed and Undisclosed Licensing Deals by Year, Aggregate Deal Value and Aggregate Upfront Payment Value, 2007–2018 87
Figure 42: Epilepsy Therapeutics Market, Global, Licensing Deals by Stage of Development, Deal Value and Upfront Payment Value, 2007–2018 88
Figure 43: Epilepsy Therapeutics Market, Global, Licensing Deals by Molecule Type and Stage of Development, 2007–2018 89
Figure 44: Epilepsy Therapeutics Market, Global, Licensing Deals by Molecular Targets and Aggregate Deal Value ($), 2007–2018 90
Figure 45: Epilepsy Therapeutics Market, Global, Co-development Deals by Region and Deal Value, 2007–2018 92
Figure 46: Epilepsy Therapeutics Market, Global, Number of Disclosed and Undisclosed Co-development Deals by Year, Aggregate Deal Value and Aggregate Upfront Payment Value, 2008–2018 93
Figure 47: Epilepsy Therapeutics Market, Global, Co-development Deals by Stage of Development, Deal Value and Upfront Payment Value, 2007–2018 94
Figure 48: Epilepsy Therapeutics Market, Global, Co-development Deals by Molecule Type and Stage of Development, 2007–2018 95
Figure 49: Epilepsy Therapeutics Market, Global, Co-development Deals by Molecular Target, 2007–2018 95