List of Figures
Figure 1: Pharmaceutical Market, Global, Innovation Trends in Product Approvals, 1987–2012 5
Figure 2: Pharmaceutical Market, Global, Sales Performance of First-in-Class and Non-First-in-Class Products Post Marketing Approval, 2006–2013 7
Figure 3: Pain Market, Global, Treatment Algorithm 15
Figure 4: Pain Market, Global, WHO Analgesic Ladder 16
Figure 5: Pain Market, Global, Marketed Products by Molecule Type and Molecular Target, 2016 18
Figure 6: Pharmaceutical Market, Global, Developmental Pipeline Overview, 2016 20
Figure 7: Pain Market, Global, Developmental Pipeline Overview, 2016 21
Figure 8: Pain Market, Global, Developmental Pipeline Molecular Target Categories, 2016 22
Figure 9: Pain Market, Global, Molecular Target Category Comparison of Pipeline and Marketed Products, 2016 23
Figure 10: Pain Market, Global, Molecular Target Category Comparison of Pipeline First-in-Class and Established Molecular Targets, 2016 25
Figure 11: Pain Market, Global, Level of First-in-Class Innovation by Stage of Development (%), 2016 26
Figure 12: Pain Market, Global, Level of First-in-Class Innovation by Molecular Target (%), 2016 26
Figure 13: Pain Market, Global, Total Pipeline Products by Pain Subtype and Stage of Development, 2016 27
Figure 14: Pain Market, Global, Total Pipeline Products by Pain Subtype and Stage of Development, 2016 27
Figure 15: Pain Market, Global, First-in-Class Pipeline Products by Pain Subtype and Molecular Target, 2016 28
Figure 16: Pain Market, Global, First-in-Class Pipeline Products by Pain Subtype and Stage of Development, 2016 29
Figure 17: Pain Market, Global, First-in-Class Products in the Pipeline Part 1, 2016 30
Figure 18: Pain Market, Global, First-in-Class Products in the Pipeline Part 2, 2016 31
Figure 19: Pain Market, Global, First-in-Class Molecular Target Analysis Matrix Part 1, 2016 33
Figure 20: Pain Market, Global, First-in-Class Molecular Target Analysis Matrix Part 2, 2016 34
Figure 21: Pain Market, Global, Pipeline Programs Targeting XXX, 2016 37
Figure 22: Pain Market, Global, Pipeline Programs Targeting XXX, 2016 37
Figure 23: Pain Market, Global, Pipeline Programs Targeting XXX, 2016 38
Figure 24: Pain Market, Global, Pipeline Programs Targeting XXX, 2016 41
Figure 25: Pain Market, Global, Pipeline Programs Targeting XXX, 2016 43
Figure 26: Pain Market, Global, Pipeline Programs Targeting XXX, 2016 44
Figure 27: Pain Market, Global, Pipeline Programs Targeting XXX, 2016 46
Figure 28: Pain Market, Global, Pipeline Programs Targeting XXX, 2016 46
Figure 29: Pain Market, Global, Pipeline Programs Targeting XXX, 2016 47
Figure 30: Pharmaceutical Market, Global, Industry-Wide Deals by Stage of Development, 2006–2014 48
Figure 31: Pharmaceutical Market, Global, Industry Licensing Deal Values by Stage of Development, 2006–2014 49
Figure 32: Pain Market, Global, Licensing Deals by Region and Value, 2006–2016 50
Figure 33: Pain Market, Global, Licensing Deals by Stage of Development and Value, 2006–2016 51
Figure 34: Pain Market, Global, Licensing Deals by Stage of Development and Molecule Type, 2006–2016 51
Figure 35: Pain Market, Global, Licensing Deals by Stage of Development and Molecular Target, 2006–2016 52
Figure 36: Pain Market, Global, Summary of Licensing Deals Valued Above $100m, 2006–2016 53
Figure 37: Pain Market, Global, Co-development Deals by Region and Value, 2006–2015 54
Figure 38: Pain Market, Global, Co-Development Deals by Stage of Development and Value, 2006–2016 55
Figure 39: Pain Market, Global, Co-Development Deals by Stage of Development and Molecule Type, 2006–2016 55
Figure 40: Pain Market, Global, Co-Development Deals by Stage of Development and Molecular Target, 2006–2016 56
Figure 41: Pain Market, Global, Summary of Co-development Deals Valued Above $100m, 2006–2016 57
Figure 42: Pain Market, Global, List of Pipeline Products With Prior Licensing or Co-Development Deal Involvement, 2016 58
Figure 43: Pain Market, Global, List of Pipeline Products Without Prior Licensing or Co-Development Deal Involvement, 2016 59