List of Figures
Figure 1: Innovation Trends in Product Approvals, 1987–2013
Figure 2: Sales Performance of First-in-Class and Non-First-in-Class Products Post Marketing Approval, 2006–2013
Figure 3: Relative Survival Rates for the Top 20 Cancers by Site, 2014
Figure 4: Molecule Types and Molecular Targets of Marketed Products for Oncology, 2015
Figure 5: Molecular Targets of Versatile Marketed Product for Oncology, 2015
Figure 6: Summary of Five-Year Survival Rate, Incidence and Mortality by Site, 2012
Figure 7: Pipeline Products by Therapy Area and Pipeline Oncology Products by Tumor Site, 2015
Figure 8: Developmental Pipeline Overview
Figure 9: Developmental Pipeline Overview by Molecular Target
Figure 10: Molecular Target Category Comparison, Pipeline and Marketed Products, 2015
Figure 11: First-in-Class Pipeline by Therapy Area and Site, 2015
Figure 12: Summary of Incidence, Mortality, Mortality Rates and Pipeline Activity by Tumor Site, 2015
Figure 13: Overview of First-in-Class Oncology Products, 2015
Figure 14: Overview of First-in-Class Oncology Products, 2015
Figure 15: Versatility of First-in-Class Oncology Pipeline Products
Figure 16: Versatility of First-in-Class Oncology Pipeline Products, as Inferred by Molecular Target
Figure 17: Versatility of First-in-Class Oncology Pipeline Products and Potential Additional Indications
Figure 18: Overview of Highly Versatile First-in-Class Pipeline Oncology Products, 2015
Figure 19: Overview of Highly Versatile First-in-Class Pipeline Oncology Products by Molecular Target, 2015
Figure 20: Molecular Target Category Comparison, Pipeline First-in-Class and Established Molecular Targets
Figure 21: Versatile First-in-Class Products in Oncology Pipeline, Part 1, 2015
Figure 22: Versatile First-in-Class Products in Oncology Pipeline, Part 2, 2015
Figure 23: Versatile First-in-Class Products in Oncology Pipeline, Part 3, 2015
Figure 24: Versatile First-in-Class Products in Oncology Pipeline, Part 4, 2015
Figure 25: Signaling Networks of Functional Families in Oncology, Part 1
Figure 26: Signaling Networks of Functional Families in Oncology, Part 2
Figure 27: Versatile First-in-Class Molecular Target Analysis Matrix, Part 1
Figure 28: Versatile First-in-Class Molecular Target Analysis Matrix, Part 2
Figure 29: Versatile First-in-Class Molecular Target Analysis Matrix, Part 3
Figure 30: Pipeline Programs Targeting Fibroblast Growth Factor Receptor-3
Figure 31: Pipeline Programs Targeting Fibroblast Growth Factor Receptor-4
Figure 32: Pipeline Programs Targeting Human Epidermal Growth Factor Receptor-3
Figure 33: Pipeline Programs Targeting Human Epidermal Growth Factor Receptor-4
Figure 34: Pipeline Programs Targeting Phosphoinositide 3-Kinase Alpha
Figure 35: Pipeline Programs Targeting Akt-1
Figure 36: Pipeline Programs Targeting Akt-2
Figure 37: Pipeline Programs Targeting Akt-3
Figure 38: Pipeline Programs Targeting Telomerase Reverse Transcriptase
Figure 39: Pipeline Programs Targeting Heat Shock Protein 90
Figure 40: Pipeline Programs Targeting Focal Adhesion Kinase
Figure 41: Pipeline Programs Targeting DNA-Dependent Protein Kinase
Figure 42: Pipeline Program Targeting Programmed Death Ligand-1
Figure 43: Industry-Wide Deals by Stage of Development, 2006–2014
Figure 44: Industry Licensing Deal Values by Stage of Development ($m), 2006–2014
Figure 45: Licensing Deals for Versatile Pipeline Oncology First-in-Class Products, 2006–2014
Figure 46: Regional Network of Licensing Deals for Versatile Pipeline Oncology First-in-Class Products, 2006–2015
Figure 47: Licensing Deals for Versatile Pipeline Oncology First-in-Class Products by Molecule Type, 2006–2015
Figure 48: Licensing Deals for Versatile Pipeline Oncology First-in-Class Products by Molecular Target, 2006–2015
Figure 49: Licensing Deals for Versatile Pipeline Oncology First-in-Class Products, 2006–2015, Part 1
Figure 50: Licensing Deals for Versatile Pipeline Oncology First-in-Class Products, 2006–2015, Part 2
Figure 51: Co-development Deals for Versatile Pipeline Oncology First-in-Class Products, 2006–2014
Figure 52: Regional Network of Co-development Deals for Versatile Pipeline Oncology First-in-Class Products, 2006–2015
Figure 53: Co-development Deals for Versatile Pipeline Oncology First-in-Class Products by Molecule Type, 2006–2015
Figure 54: Co-development Deals for Versatile Pipeline Oncology First-in-Class Products by Molecular Target, 2006–2015
Figure 55: Co-development Deals for Versatile Pipeline Oncology First-in-Class Products, 2006–2015