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Innovation Tracking Factbook 2018: An Assessment of the Pharmaceutical Pipeline

  • Published: Dec-2018
  • Report Code: GBI094CBR
  • Report Format: pdf

Description

Table of Contents

1 Table of Contents 3

1.1 List of Tables 4

1.2 List of Figures 4

2 Introduction 6

2.1 Increasing Cost of Drug Development 9

2.2 Most Drugs Fail to Recuperate R&D Costs 10

2.3 Contracting Life Cycles for Approved Products 11

2.4 The Case for First-in-Class Pharmaceutical Innovation 13

2.5 Status of Innovation in Rare Diseases 14

2.6 Conclusion 16

3 Assessment of Pharmaceutical Industry Pipeline 17

3.1 Pipeline and Clinical Trials Landscape by Therapy Area 18

3.2 Pipeline by Stage of Development 24

3.3 Pipeline by Molecule Type 26

3.4 Key Therapy Areas by Indication 30

3.4.1 Oncology 30

3.4.2 Infectious Diseases 32

3.4.3 Central Nervous System 34

3.4.4 Immunology 36

3.5 Conclusion 38

4 Assessment of Innovation in the Pharmaceutical Industry Pipeline 39

4.1 First-in-Class Innovation by Stage of Development 42

4.2 Key Therapy Areas by Indication 43

4.2.1 Oncology 43

4.2.2 Infectious Diseases 46

4.2.3 Central Nervous System 49

4.2.4 Immunology 52

4.3 Conclusion 54

5 Appendix 55

5.1 References 55

5.2 Abbreviations 56

5.3 Contact Us 56

5.4 Disclaimer 57

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